Other treatments are directed toward helping the symptoms and avoiding complications.
There are no direct therapies for enteric neuropathies and ASCENT would be the first cellular therapy for a broad class of severe disease including Hirschsprung disease and other enteric neuropathies that are morbid and mortal. With our stem cell therapy, we harvest the stem cells from your bone marrow and redirect them to where you need them most. Researchers at Duke University say an experimental stem cell therapy being tested on animals shows great potential to provide long-lasting pain relief for people suffering from diabetic neuropathy or other types of nerve damage. Patients with autoimmune neuropathy are sometimes treated with aggressive therapies such as: Intravenous immune globulin. (MSC2) attenuate symptoms of painful diabetic peripheral neuropathy, Stem Cells Translational Medicine, vol. ASCENT - Advanced Superdonor Cellular Enteric Neuropathy Therapy, is a donor progenitor cell population that, after transplantation in vivo, replaces absent functional ENS components. Several papers have been written on experimental neuropathic pain treatment using stem cells of different origin and species to treat experimental NP. We propose to generate a cellular therapy from the starting material of “superdonor” human iPS cell lines. Research in the past decade has demonstrated that adipose-derived stem and regenerative cells (ADRCs) are effective at promoting nerve repair and thus have the. Our goal is to develop an allogeneic “off the shelf” cellular therapy to treat enteric neuropathies before surgical interventions are needed or to rescue patients in whom effects of the ENS defect persist. Stem cells are showing great potential as a viable alternative for those seeking to better manage their neuropathy. Stem cell therapy can help relieve your pain from peripheral neuropathy. ASCENT - Advanced Superdonor Cellular Enteric Neuropathy Therapy, is a donor progenitor cell population that replaces the enteric nervous system.ĪSCENT would treat enteric neuropathies including Hirschsprung disease and total intestinal aganglionosis which currently have no direct therapy
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